Dr. Alessio Fasano, MD is Professor of Pediatrics at Harvard Medical School, Professor of Nutrition at Harvard T.H. Chan School of Public Health, and Director of the Mucosal Immunology and Biology Research Center at Massachusetts General Hospital in Boston, Massachusetts. Dr. Fasano’s translational science is focused on the role of impaired intestinal barrier function in the pathogenesis of autoimmune and inflammatory diseases, including celiac disease, autism and type 1 diabetes. Director of the Center for Celiac Research and Treatment at (MGHfC), Dr. Fasano is widely sought after as an expert in celiac disease, intestinal permeability and autoimmune disorders.
00:00 Introduction
03:02 Ancient microbiome evidence
04:38 Evolutionary mismatches in modern human microbiome
08:37 Differences in hunter gatherer vs civilized health
11:38 Factors in disease
15:48 Zonulin
17:55 Microbes affecting intestinal permeability
19:01 Antibiotics
24:18 How to maintain healthy microbiome
27:07 Treating disease with nutrition
33:36 How do we build health starting as children
36:19 Changing the culture towards health
38:56 Microbiome connection to child behavioral disorders
41:33 We’re still learning about microbiome
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